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Erschienen in: Current Urology Reports 2/2021

01.02.2021 | Men's Health (R Carrion, Section Editor)

Conservative Therapy for Peyronie’s Disease: a Contemporary Review of the Literature

verfasst von: Ayad Yousif, Caleb Natale, Wayne J. G. Hellstrom

Erschienen in: Current Urology Reports | Ausgabe 2/2021

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Abstract

Purpose of Review

To analyze the literature on current conservative treatment options for Peyronie’s disease (PD).

Recent Findings

Conservative therapy with intralesional collagenase clostridium histolyticum (CCH) is safe and efficacious in either the acute or chronic phases of PD. Combination treatment with penile traction therapy (PTT) can produce even better results. While most PTT devices require extended periods of therapy up to 8 h per day, the RestoreX® device can be effective at 30–90 min per day.

Summary

A variety of conservative therapies are available for treatment of PD. The available literature does not reveal any treatment benefit of oral therapies. Intralesional therapy is the mainstay conservative treatment of PD. Intralesional CCH therapy is the first Food and Drug Administration-approved intralesional therapy and represents the authors’ preference for medical therapy. The most effective conservative management of PD likely requires a combination of therapies.
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Metadaten
Titel
Conservative Therapy for Peyronie’s Disease: a Contemporary Review of the Literature
verfasst von
Ayad Yousif
Caleb Natale
Wayne J. G. Hellstrom
Publikationsdatum
01.02.2021
Verlag
Springer US
Erschienen in
Current Urology Reports / Ausgabe 2/2021
Print ISSN: 1527-2737
Elektronische ISSN: 1534-6285
DOI
https://doi.org/10.1007/s11934-020-01024-8

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